Effectiveness of artificial ventilation in oil microembolism followed by pulmonary edema
Tarakanov, I.A.; Kuz'michev, S.A.; Semkina, G.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 114(7): 18-19
1992
ISSN/ISBN: 0365-9615 PMID: 1421295 Document Number: 404174
In experiments on sodium pentobarbital (40 mg/kg, i.p.) anesthetized mongrel cats of either sex weighting from 2.0 to 4.0 kg, it was found, that in conditions of oil pulmonary microembolization, followed by pulmonary edema, the most suitable is rapid and shallow pattern of ventilation, ensuring optimal ventilation/perfusion interrelation. The oil microembolization was introduced with intravenous administration (1 mg per kg of body weight during 2 min) of olive oil. It is necessary to provide flexible regimens of artificial ventilation and conformity of respiratory pattern and body's demands can be controlled according to pHa and PaO2. It is desirable that pH and pO2 can be evaluated continuously.