Tumor necrosis factor and interleukin 6 in hepatitis C virus infection
Ren, H.; Zheng, D.F.; Jia, X.P.
Zhonghua Nei Ke Za Zhi 31(6): 344-346; 381
1992
ISSN/ISBN: 0578-1426 PMID: 1286584 Document Number: 404012
Tumor necrosis factor (TNF) was determined with ELISA in 72 patients with hepatitis C and hepatitis B virus infections. Interleukin 6 (IL-6) was determined at the same time. TNF and IL-6 were significantly increased in patients with hepatitis C virus infections when compared with normal subjects and hepatitis B patients. There was a significant positive correlation between TNF and IL-6. It is suggested that increased TNF and IL-6 may play an important role in pathogenesis of hepatitis C virus infection.
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