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The factors that affect the results of the serological diagnosis of HIV infection and the screening for anti-HIV

Vasil'eva, V.I.; Iakhno, K.V.; Medvedeva, G.I.; Kozhevnikova, L.K.; Pakhomova, A.N.; Ivanova, M.I.

Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 1992(11-12): 20-23

1992

ISSN/ISBN: 0869-6047
PMID: 1284215
Document Number: 403578
The laboratory diagnosis of HIV infection and screening for anti-HIV have determined the factors that influence the results of studies performed by ELISA and Western immunoblot. The factors include sensitivity and specificity of the test systems used, storage conditions of and transportation conditions for serum, errors of procedures for reactions, etc. Correlation is between the inactivation of the sera studied and the initial antibody titers during their storage at elevated temperatures. To obtain more valid results of HIV infection serodiagnosis it is necessary to use some test systems differing in the principles of setting up a reaction.

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