Prognostic value of histopathological parameters in epidermoid carcinoma of the vocal cords in T-1 stage
Barona, R.; Basterra, J.; Martorell, M.A.; Garín, L.; Alvarez-Valdés, R.; Armengot, M.
Anales Otorrinolaringologicos Ibero-Americanos 19(5): 467-474
1992
ISSN/ISBN: 0303-8874 PMID: 1443465 Document Number: 403407
In this paper are studied macro- and microscopically, 14 histopathologic parameters belonging to 37 patients suffering from vocal cord squamous cell carcinoma, stage T-la. All patients were submitted to cordectomy and followed up during a 5 years term, as a minimum. A discriminant analysis was performed in order to establish the relation between histopathologic parameters and local failure. Only two of them were statistically significative (p < 0.01): the structural type and the differential degree of tumor cells. The histopathological study allowed the prediction of 82 percent of local recurrences.