Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effects of smoking on fetoplacental-maternal system during pregnancy

Mochizuki, M.; Maruo, T.; Masuko, K.; Ohtsu, T.

American Journal of Obstetrics and Gynecology 149(4): 413-420

1984

ISSN/ISBN: 0002-9378
PMID: 6203408
DOI: 10.1016/0002-9378(84)90156-x
Document Number: 403405
Fetoplacental function and maternal nutritional status were assessed in order to clarify the mechanism of retarded fetal growth in pregnant women who smoked. Dehydroepiandrosterone sulfate (DHA-S) loading tests and measurements of cotinine, a major metabolite of niccotine, were also made. In heavy smokers, urinary estriol and serum levels of human placental lactogen (hPL) were lower than those in nonsmokers. There was no difference in maternal nutrition between smokers and nonsmokers. Heavy smokers demonstrated a lower conversion of DHA-S to estradiol than did nonsmokers. Levels of cotinine in maternal blood and umbilical cord blood of heavy smokers were remakably higher than those in nonsmokers. Microscopic examination showed atrophic and hypovascular changes in placental villi from mothers who smoked. These results suggest that retarded fetal growth in heavy smokers is due to impairment of uteroplacental circulation as a ressult of the vasoconstricting effect of nicotine.

Document emailed within 0-6 h
Secure & encrypted payments

Hercz, P. 1985: Quantitative changes in steroid and peptide hormones in the maternal-fetoplacental system between the 28th-40th weeks of pregnancy Acta Medica Hungarica 42(1-2): 29-39
Mochizuki, M.; Morikawa, H.; Mizutani, M.; Chough, S.Y.; Tojo, S. 1971: Effects of human chorionic somatotropin (HCS:HPL) on fetoplacental maternal system in starvation Nihon Sanka Fujinka Gakkai Zasshi 23(9): 864-865
Hercz, P.; Siklós, P.; Ungár, L. 1987: Serum cortisol level changes in the maternal-fetoplacental unit between the 28th-40th weeks of pregnancy Acta Physiologica Hungarica 69(2): 161-165
Jouppila, P.; Kirkinen, P.; Koivula, A.; Ylikorkala, O. 1985: Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids Obstetrics and Gynecology 65(1): 115-118
Timoshenko, L.V.; Lial'kina, A.I. 1980: Biological rhythms of the fetoplacental system in normal and prolonged pregnancy Akusherstvo i Ginekologiia 19(5-6): 416-420
Nesterova, A.A.; Bakuleva, L.P.; Iakutina, M.F. 1978: Functional diagnostic tests of the fetoplacental system in high-risk pregnancy Akusherstvo i Ginekologiia 5: 43-45
Stjernfeldt, M.; Ludvigsson, J.; Berglund, K.; Lindsten, J. 1986: Maternal smoking during pregnancy and the risk of childhood cancer Lancet 2(8508): 687-688
Lee, J.N.; Grudzinskas, J.G.; Chard, T. 1981: Effect of smoking on maternal blood SP1 levels in late pregnancy Obstetrics and Gynecology 57(2): 220-223
Rashid, M.; Rashid, H. 2003: Passive maternal smoking and pregnancy outcome in a Saudi population Saudi Medical Journal 24(3): 248-253
Bernstein, L.; Pike, M.C.; Lobo, R.A.; Depue, R.H.; Ross, R.K.; Henderson, B.E. 1989: Cigarette smoking in pregnancy results in marked decrease in maternal hCG and oestradiol levels British Journal of Obstetrics and Gynaecology 96(1): 92-96
Polańska, K.; Hanke, W. 2004: Effect of smoking during pregnancy on maternal condition and birth outcome--overview of epidemiologic studies Przeglad Epidemiologiczny 58(4): 683-691
Liu, T.; Chen, W-Qing.; He, Y-Hui.; Ding, P.; Ling, W-Hua. 2009: A meta-analysis on the association between maternal passive smoking during pregnancy and small-for-gestational-age infants Zhonghua Liu Xing Bing Xue Za Zhi 30(1): 68-72
Dunn, H.G.; McBurney, A.K.; Sandraingram; Hunter, C.M. 1977: Maternal cigarette smoking during pregnancy and the child's subsequent development: II. Neurological and intellectual maturation to the age of 6 1/2 years Canadian Journal of Public Health 68(1): 43-50
Eriksen, P.S.; Gennser, G.; Löfgren, O.; Nilsson, K. 1983: Acute effects of maternal smoking on fetal breathing and movements Obstetrics and Gynecology 61(3): 367-372
Cooper, A.R.; Moley, K.H. 2008: Maternal tobacco use and its preimplantation effects on fertility: more reasons to stop smoking Seminars in Reproductive Medicine 26(2): 204-212
Tager, I.B.; Weiss, S.T.; Muñoz, A.; Rosner, B.; Speizer, F.E. 1983: Longitudinal study of the effects of maternal smoking on pulmonary function in children New England Journal of Medicine 309(12): 699-703
Morrow, R.J.; Ritchie, J.W.; Bull, S.B. 1988: Maternal cigarette smoking: the effects on umbilical and uterine blood flow velocity American Journal of Obstetrics and Gynecology 159(5): 1069-1071
Goriachev, V.V. 1984: Maternal and fetal serum aminotransferase and aldolase activities in chronic fetoplacental insufficiency Sovetskaia Meditsina 4: 48-51
Goel, P.; Radotra, A.; Singh, I.; Aggarwal, A.; Dua, D. 2004: Effects of passive smoking on outcome in pregnancy Journal of Postgraduate Medicine 50(1): 12-16
Gray, D.; Czövek, D.; Smith, E.; Willemse, L.; Alberts, A.; Gingl, Z.án.; Hall, G.L.; Zar, H.J.; Sly, P.D.; Hantos, Z.án. 2015: Respiratory impedance in healthy unsedated South African infants: effects of maternal smoking Respirology 20(3): 467-473