Converting enzyme inhibitors in diabetes
Marre, M.
La Revue du Praticien 42(20): 2574-2577
1992
ISSN/ISBN: 0035-2640 PMID: 1299943 Document Number: 402301
ACE inhibitors are used on a large scale basis in hypertensive diabetics, while the association between diabetes and hypertension is frequent and harmful. This is due to their excellent tolerance and efficacity. No specific advantage has been reported in their use regarding tolerance, i.e., they may not alter insulin sensitivity consistently. Conversely, ACE inhibitors may offer the specific advantage of protecting kidney function against diabetic microangiopathy, since their effects on glomerular haemodynamics seem independent from their hypotensive effect.