The significance of the content of connective tissue metabolites in the blood serum for the diagnosis of chronic viral hepatitis and liver cirrhosis
Smirnov, B.M.; Trishkova, L.A.
Likars'ka Sprava 1: 81-84
1992
ISSN/ISBN: 1019-5297 PMID: 1364619 Document Number: 402148
With the purpose of improving early clinico-biochemical diagnosis of viral chronic active hepatitis and liver cirrhosis in children, the authors used indices of connective tissue metabolism--determination of free oxiprolin and neutral lipids in the blood serum. High levels of free oxiprolin and neutral lipids were revealed in patients with chronic active hepatitis and low--in liver cirrhosis. These data characterize different reactions of the connective tissue in the named diseases determined by different morphological maturity grades and secretory activity of fibroblasts.