Inhibition of gastric motility by endotoxin (bacterial lipopolysaccharide) in conscious goats and modification of this response by splanchnectomy, adrenalectomy or adrenergic blocking agents

van Miert, A.S.

Archives Internationales de Pharmacodynamie et de Therapie 193(2): 405-414

1971


ISSN/ISBN: 0003-9780
PMID: 4940881
Document Number: 40133
Endotoxin from E. coli O111:B4 strongly inhibited gastric contractions in goats, and this inhibition was not affected by adrenergic blocking agents, adrenalectomy or splanchectomy. Alpha-methyldopa (Aldomet), an inhibitor of catecholamine synthesis, had an antipyretic action in goats but not in rabbits.

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