The results of a retrospective examination of patients with acute rheumatic fever
Dzhuzenova, B.S.; Kotel'nikova, G.P.; Nesterova, N.I.; Nasonova, V.A.
Terapevticheskii Arkhiv 64(5): 88-93
1992
ISSN/ISBN: 0040-3660 PMID: 1455387 Document Number: 401192
The authors describe the results obtained during retrospective examinations of 45 subjects who suffered from acute rheumatic fever 10-14 years before. Of these, 19 subjects were treated with prednisolone in the acute disease period, 16 with indometacin, and 8 subjects with voltaren. The examinations were mostly randomized (30 subjects); no differences in the antiinflammatory effect were discovered. Heart disease was found in 9 persons (20%). Of these, 6 were treated with prednisolone, 2 with indometacin, and 1 with voltaren. The disease relapses were recorded in 4 of them, the signs of valvulitis in the past were shown only by 2 persons (echocardiographically). 12 persons (27%) had mitral valve prolapse which had not been diagnosed on the first admission to the hospital, with any clinical signs of hypermotility lacking. In 18 persons (40%) having no valve lesions (disease, prolapse), an x-ray examination revealed a slight increase of the heart size, estimated as a manifestation of postmyocarditic cardiosclerosis. Thus, it has been shown that modern antiinflammatory therapy does not prevent the development of heart disease. Apparently, its onset is related to specific proneness is some of the patients.