Evaluation of the effectiveness of prazosin in conservative treatment of benign prostatic hypertrophy
Górecki, R.; Krzeski, T.; Wasik, J.; Borówka, A.
Polski Tygodnik Lekarski 47(24-26): 549-551
1992
ISSN/ISBN: 0032-3756 PMID: 1282713 Document Number: 399045
Prazosin--a selective blocker of alpha 1-adrenergic receptors--was administered to 30 patients with benign prostatic hypertrophy. Twenty four patients (80%) reported an improvement in voiding and observed more potent urinary stream after the treatment. Average and maximum flow rates increased in 18 patients (60%). Therapy had to be discontinued in 2 patients because of the adverse reactions (hypotension and syncope in one and exacerbation of the coronary disease symptoms in another patient).