Inhibition of cytokinesis by lead (Pb2+) in a centric diatom
Giri, B.S.; Devi, N.A.
Indian Journal of Experimental Biology 30(3): 201-204
1992
ISSN/ISBN: 0019-5189 PMID: 1512027 Document Number: 398512
Effect of inorganic and organo lead has been studied on the mitosis of a centric diatom Cyclotella meneghiniana f. unipunctata. Binucleate cells were formed in the presence of different concentrations of Pb2+ (1.0, 2.0, 3.0 and 5.0 mM) due to inhibition of cell plate formation. Lead at 5.0 mM concentration was more inhibitory than the other concentrations. Organo lead was a powerful depressant of cytokinesis than inorganic lead. Failure of cytokinesis might be due to disruption of microtubules. Formation of distinct nuclei delayed post incubation cell divisions suggest partial damage of mitotic spindles.