Subpopulation state of T and B lymphocytes in hemolytic-uremic syndrome in children
Tebloeva, L.T.; Riabchikov, O.P.; Surkova, G.N.
Pediatriia 3: 35-39
1992
ISSN/ISBN: 0031-403X PMID: 1513649 Document Number: 398095
A study was made of the quantitative characteristics of T and B lymphocytes and of their subpopulations (A-RFC; E37-RFC; auto-RFC; EAC-RFC; Ig(+)-cells) as well as of 0-lymphocytes in the peripheral blood of 20 children aged 6 to 24 months with different clinical stages of the hemolytic-uremic syndrome (oligoanuria, diuresis onset, polyuria, clinical improvement). It is concluded that all the stages of the disease are characterized by the deficiency of certain subpopulations of T cells (especially A-RFC, E37-RFC), B lymphocytes, and 0-cells. By the moment of the clinical improvement, the cellular characteristics of the immune status do not return to normal.