Application of derivative resolution of UV spectra to the quality control of rifaximine and its possible impurities
Corti, P.; Savini, L.; Celesti, L.; Ceramelli, G.; Montecchi, L.
Pharmaceutica Acta Helvetiae 67(3): 76-79
1992
ISSN/ISBN: 0031-6865 PMID: 1589440 Document Number: 397443
An UV spectrophotometric method with derivative resolution was developed for the analysis of rifaximine (a synthetic rifamycin) in the presence of potential impurities of synthesis and oxidation. The method was particularly suitable for the qualitative identification of the set of compounds and had good detection limits.
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