Allergic reactions to teniposide (VM-26) in children with neoplasms
Wysocki, M.; Nowaczyk-Michalak, A.; Pilecki, O.
Wiadomosci Lekarskie 45(3-4): 91-93
1992
ISSN/ISBN: 0043-5147 PMID: 1413803 Document Number: 397411
Allergic reactions of dramatic intensity were observed in 5 children treated with Teniposide (VM-26) for acute lymphoblastic leukaemia and histiocytosis X. In the further treatment this drug was replaced with epoxide, a cytostatic agent which is also a podophyllin derivative but in other chemical formulation. In none of these patients the allergic reaction returned.