Teratological examination of the insecticide methyl-parathion (Wofatox 50 EC) on pheasant embryos. 2. Biochemical study
Várnagy, L.
Acta Veterinaria Hungarica 40(3): 203-206
1992
ISSN/ISBN: 0236-6290 PMID: 1298166 Document Number: 394853
Fertile pheasant eggs were treated with the insecticide Wofatox 50 EC (50% methyl-parathion) on day 12 of the hatching period. Treatment consisted of inoculation of 0.1 ml of different concentrations of the insecticide into the air space of embryonated eggs. The following dose levels were employed: 0.00, 1.35, 13.5 and 135 mg/kg egg of active ingredient. Biochemical changes in the plasma were evaluated by micro (photometric) methods which rendered possible the determination of several blood plasma variables of the embryos. At the highest dose level applied, serum alkaline phosphatase (SAP) enzyme activity and inorganic P concentration of the treated embryos showed decreases when compared to the controls. Macroscopic alterations were detected at PM examinations including malformations (lordoscoliosis, cyllosis).