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Chinese strategies for hepatitis B virus markers screening in hepatitis B vaccination based on cost-effectiveness analysis

Zhang, S.X.

Zhonghua Yu Fang Yi Xue Za Zhi 26(3): 154-158

1992

ISSN/ISBN: 0253-9624
PMID: 1395956
Document Number: 394636
By means of decision tree model and cost-effectiveness analysis 15 kinds of programmes which may be used for hepatitis B virus markers screening in vaccination were evaluated. The results showed that the most cost-effective alternative was to identify the negatives for anti-HBc again after testing for anti-HBs and vaccinating all test negatives. That is to say it must not be adopted for persons to be tested for HBsAg, anti-HBs and anti-HBc before being vaccinated. Sensitivity and threshold analysis were also done to determine the effects of changes in the costs of vaccine and screening tests.

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