Simultaneous identification of the nucleolar organizing regions and G bands in obstetrical cytogenetic studies
Aguilar Parada, E.; Rábago Velasco, M.; Espinosa Torres, M.
Ginecologia y Obstetricia de Mexico 60: 277-280
1992
ISSN/ISBN: 0300-9041 PMID: 1427286 Document Number: 394584
An improvement of the silver-staining method of the nucleolus organizer region with simultaneous trypsin-Giemsa-banding is described. The combined demonstration of such regions (which express the transcriptive activity of ribosomal ribonucleic acid genes) and the precise identification of chromosomes, particularly acrocentric chromosomes, should be of value in the investigation of parents with spontaneous abortion in whom abnormal acrocentric chromosomes are often encountered.