Neurohistological characteristics of regeneration of the ends of the injured nerve under measured traction
Ilizarov, G.A.; Shudlo, M.M.; Kuznetsova, A.V.; Shudlo, N.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 113(4): 439-442
1992
ISSN/ISBN: 0365-9615 PMID: 1391914 Document Number: 394272
A resection of sciatic nerve in 25 dogs was performed out and the ends of cut nerve were connected by sutures with special apparatus for quantified traction of nerve stumps. 5 days after resection traction was stented at the rate of 0.25 mm twice a day. A histological analysis performed in 5, 12, 19, 26, 33 days after resection an 2-12 months after nerve suture has shown that stress strain effects on intercalation of nerve structures (Ilizarov's effect). Newly formed Schwann chains free of products of axonal and myelin disruption have got a perfect longitudinal orientation and that's why can be considered as an optimum substratum for axonal regeneration.