Dihydroergocryptine in the management of senile psycho-organic syndrome
Scarzella, L.; Bono, G.; Bergamasco, B.
International Journal of Clinical Pharmacology Research 12(1): 37-46
1992
ISSN/ISBN: 0251-1649 PMID: 1526697 Document Number: 394112
A double-blind, placebo-controlled, randomized study is described of an assessment of the efficacy and relative safety of the ergot alkaloid, dihydroergocryptine, on 52 patients with mild organic brain syndrome over a period of three months using a series of neurophysiological tests. The results indicated that short-term treatment with the alkaloid improved memory impairment. The side-effects were mild and transient in both the dihydroergocryptine and placebo groups and there were no alterations in blood chemistry.