Competitive new generation myorelaxants in pediatric neuroanesthesia
Gifuni, D.; Frangiosa, A.; Geri, A.; Graziano, D.V.
Minerva Anestesiologica 58(4 Suppl 1: 197-200
1992
ISSN/ISBN: 0375-9393 PMID: 1352392 Document Number: 392477
Two groups of 50 children were included in a study to examine the use of atracurium and vecuronium. In both groups, newborns and infants showed a shorter onset time and a longer clinical duration of the first dose of the neuromuscular blocking drug. The duration of subsequent doses in the various age groups was not significantly different. Atracurium and vecuronium both have a short recovery index, good cardiovascular stability and do not interfere with ICP. The Authors emphasise the importance of monitoring the use of neuromuscular blocking drugs.