Long-term use of gamma-linolenic acid-enriched fat emulsion (PFE 4501) : case report
Söreide, E.; Skeie, B.; Katz, D.P.; Manner, T.; Askanazi, J.
Nutrition 8(3): 182-185
1992
ISSN/ISBN: 0899-9007 PMID: 1326350 Document Number: 392131
A new gamma-linolenic acid-enriched fat emulsion (PFE 4501) was given for 13 mo as part of a home parenteral nutrition regimen to a 28-yr-old patient with cystic fibrosis. Blood biochemistry, hematological data, and fatty acid profile were followed. No side effects were reported, and pulmonary function tests remained stable. gamma-Linolenic acid appears to be safe for clinical use and may benefit patients with derangements in essential fatty acid metabolism. The potential role of a gamma-linolenic acid-enriched intravenous fat emulsion is discussed.