Syphilitic gastritis in an HIV-infected individual
Kasmin, F.; Reddy, S.; Mathur-Wagh, U.; Sarlin, J.; Goldman, A.; Antosofsky, H.; Strutynsky, N.
American Journal of Gastroenterology 87(12): 1820-1822
1992
ISSN/ISBN: 0002-9270 PMID: 1449150 Document Number: 391529
We report the first known case of syphilitic gastritis in an HIV-infected person. The presentation of nonspecific abdominal pain and weight loss in a 48-yr-old former intravenous drug user previously treated for asymptomatic syphilis led to a barium swallow which demonstrated linitis plastica. Upper endoscopy reinforced a suspicion of carcinoma, but biopsy made the diagnosis of syphilis by silver staining. Further testing revealed a positive serology for syphilis as well as HIV infection with a depressed CD-4 lymphocyte count. Treatment with parenteral penicillin led to a rapid resolution of symptoms. This case represents a rare complication of late syphilis, and is another example of the unusual manifestations of syphilis seen in the HIV-infected population.