Adenosine and carnitine derivatives and calcium movements in rat heart sarcoplasmic reticulum
Bertelli, A.; Ronca-Testoni, S.; Spaggiari, P.G.; Zucchi, R.
International Journal of Tissue Reactions 14(1): 11-15
1992
ISSN/ISBN: 0250-0868 PMID: 1399317 Document Number: 391489
Many researches indicate that some Ca antagonists modulate Ca fluxes not only at the level of the cytoplasmic membrane but also across the sarcoplasmic reticulum. The present study investigates whether certain compounds like propionylcarnitine or acetylcarnitine which have the capacity to influence cardiac activity might interfere with intracellular Ca movements. The results demonstrate that acetylcarnitine and propionylcarnitine do not affect the calcium intracellular movement in sarcoplasmic reticulum.