How pyridoxal 5'-phosphate could function in glycogen phosphorylase catalysis

Helmreich, E.J.

Biofactors 3(3): 159-172

1992


ISSN/ISBN: 0951-6433
PMID: 1599610
Document Number: 391460
The role of pyridoxal 5'-phosphate in glycogen phosphorylase catalysis is reviewed under the headings: Experiments and interpretations concerning the role of pyridoxal phosphate in glycogen phosphorylase; Ionization changes of the phosphate group of pyridoxal phosphate on transition from inactive to active phosphorylase; Studies with glycosylic substrates; The amino acids participating in catalysis; and A mechanism for the phosphorylase reaction requiring the participation of pyridoxal 5'-phosphate.

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