Cushing syndrome in a neuroendocrine pancreatic tumor. Clinicopathologic case report
Schneider, C.; Mittelmeier, H.O.; Gebhardt, C.
Leber Magen Darm 22(6): 234-236
1992
ISSN/ISBN: 0300-8622 PMID: 1336088 Document Number: 391273
A 59-year-old female patient with mild clinical features of a Cushing syndrome underwent surgery for a suspected hormonally active tumor of the left adrenal gland. Surprisingly, the adrenal gland was unremarkable, however, a tumor in the pancreatic tail was found. A left pancreatic resection with splenectomy resulted in curative removal of the tumor. The pathohistological examination of the tumor established the diagnosis of an ACTH-producing pancreatic carcinoid. Morphology and pathogenesis of pancreatic carcinoids which are tumors of the APUD-cell-system are discussed in detail.