Involvement of cellular division cycle in the susceptibility of Escherichia coli to cold- and osmotic-shock
Hodgson, A.; Evans, D.J.; Brown, M.R.; Gilbert, P.
Microbios 72: 292-293
1992
ISSN/ISBN: 0026-2633 PMID: 1488019 Document Number: 390557
Susceptibility of Escherichia coli to cold-shock, osmotic-shock and cold-osmotic-shock has been evaluated throughout the cellular division cycle for a variety of generation time. Two periods of sensitization were detected. The first of these was towards cold-shock which occurred 60 min prior to cell division and might correspond to initiation of DNA replication. The second period of sensitization was towards both cold-, osmotic- and cold-osmotic-shock and occurred immediately prior to and during cell division. Patterns and extents of sensitization towards each of these three stresses during the second period were suggestive of a common sensitizing event associated with constriction of the cell and separation.