Role of ciprofloxacin in typhoid fever
Akhtar, M.A.; Hussain, A.; Karamat, K.A.; Naqi, N.; Zubdi, N.
Jpma. Journal of the Pakistan Medical Association 42(1): 9-10
1992
ISSN/ISBN: 0030-9982 PMID: 1545485 Document Number: 389084
A study was conducted to investigate the effects of ciprofloxacin in typhoid fever and to compare its efficacy with chloramphenicol. Eighty patients between 20-45 years with positive blood culture were included in the study. Seventy five percent patients treated with ciprofloxacin became afebrile within 72 hours while with chloramphenicol it took upto 120-144 hours for the same percentage of patients to become afebrile. Four patients resistant to chloramphenicol, cotrimoxazole and ampicillin/amoxycillin, also responded to ciprofloxacin. There were no significant adverse effects indicating that ciprofloxacin is safe and effective drug for resistant and nonresistant cases of typhoid fever.