Local estrogen premedication reduces the abortion time in prostaglandin E1 analogue-induced abortion in the 2nd trimester
Petersen, L.K.; Uldbjerg, N.; Allen, J.G.
Ugeskrift for Laeger 153(21): 1486-1487
1991
ISSN/ISBN: 0041-5782 PMID: 2053197 Document Number: 387678
Twenty-eight patients (median gestational age 17 weeks) referred for induction of second trimester abortion, were randomized to intracervical preliminary treatment by either 50 mg 17 beta-oestradiol or placebo. Abortion was then induced by 1 mg prostaglandin E1 vagitories. The preliminary treatment caused a significant rise in cervical score and a significant reduction in induction-abortion time especially by reducing the number of patients with prolonged induction-abortion time.