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Secondary hyperparathyroidism caused by oral contraceptives

Moses, A.M.; Notman, D.D.

Archives of Internal Medicine 142(1): 128-129

1982

ISSN/ISBN: 0003-9926
PMID: 6274264
DOI: 10.1001/archinte.1982.00340140130020
Document Number: 387064
Secondary hyperparathyroidism developed on two separate occasions in a patient taking an oral contraceptive (OC) in a mixture of norethindrone and mestranol (Ortho-Novum 1/80). The probable cause of this condition is an estrogenic inhibition of the calcium mobilizing effect of parathyroid hormone (PTH) or vitamin D. The possible consequences of OC therapy in this patient and patients like her include those of milk hypocalcemia, moderate hypophosphatemia, or the neurotoxic actions of excessive levels of circulating PTH. One should also consider the possible role of OC therapy in patients with unexplained parathyroid hyperplasia and with tertiary hyperparathyroidism.

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Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives : levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception (Stoneham) 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292
Jick, S.S.; Jick, H. 2006: Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch Contraception 74(4): 290-292