T-lymphocyte subpopulations in chronic active hepatitis
Fucíková, T.; Brodanová, M.; Bartůnková, J.; Skopový, P.; Hausner, P.; Krupicka, J.
Sbornik Lekarsky 93(1-2): 27-32
1991
ISSN/ISBN: 0036-5327 PMID: 2047739 Document Number: 386146
In 33 patients with chronic active hepatitis quantitative changes were found in the ratio of different sub-populations of T lymphocytes in the peripheral blood stream which were either associated with treatment or with the presence of HbsAg in serum. A reduction of CD 3 positive lymphocytes was found in patients not treated by immunosuppression. In HbsAg positive patients an increase of CD 4 positive lymphocytes was found, as compared with HBsAg negative patients. Signs of activity of the hepatic process correlated with the presence of sign CD 8.