Cerebral glucose metabolism in schizophrenia. Studies using positron-emission tomography
M'Rabet, N.; Lotstra, F.; Goldman, S.; Delvenne, V.; Mendlewicz, J.
Acta Psychiatrica Belgica 91(6): 311-326
1991
ISSN/ISBN: 0300-8967 PMID: 1670424 Document Number: 385135
Several studies using positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG) have revealed functional hypofrontality in schizophrenia. However, frontal hypometabolism is not consistently found and is not specific to schizophrenia. Basal ganglia glucose hypermetabolism related to neuroleptic treatment has been demonstrated. Methodological and clinical differences between studies are discussed in this paper.
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