Diabetes mellitus induced in a dog after administration of corticosteroids and methylprednisolone pulse therapy
Jeffers, J.G.; Shanley, K.J.; Schick, R.O.
Journal of the American Veterinary Medical Association 199(1): 77-80
1991
ISSN/ISBN: 0003-1488 PMID: 1885333 Document Number: 384630
An 8-year-old ovariohysterectomized Chow Chow was referred because of dermatologic lesions diagnosed as pemphigus foliaceus. Intolerance to orally administered corticosteroids necessitated the use of methylprednisolone pulse therapy. One week after treatment, diabetes mellitus was diagnosed on the basis of blood and urine test results. For 3 years after treatment, the dog has remained a well-regulated diabetic. Complete remission of pemphigus foliaceus is maintained by alternate-day, orally administered prednisone (0.5 mg/kg of body weight).