Aerosol deposit sample in aspecific bronchial provocation test: a nuclear medicine study for quantification
Eltschka, R.; App, E.; Köhler, D.; Popov, T.; Matthys, H.
Pneumologie 45(Suppl 2): 654-658
1991
ISSN/ISBN: 0934-8387 PMID: 1946272 Document Number: 382142
A method of standardization of inhalation bronchial provocation tests is induced. The distribution of radioactivity of in- and exhaled 99mTc human albumin (Venticoll) enables an exact calculation of intrabronchial aerosol deposition. The investigations were carried out at twelve normal test persons by using the device of bronchial provocation tests of PARI. Linearity exists between nebulized aerosol quantity in the bag and bronchial aerosol deposition. The intrabronchial aerosol deposition is calculated about 100 mg after emptying the ten liter-bag. Slowly inspiratory maneuvers of vital capacity produce a precision of the inhaled aerosol of about 15 percent.