Randomised clinical trials with clinician-preferred treatment
Korn, E.L.; Baumrind, S.
Lancet 337(8734): 149-152
1991
ISSN/ISBN: 0140-6736 PMID: 1670796 Document Number: 381632
The standard design for randomised clinical trials may be inappropriate when the clinican believes that one of the treatments being testing is superior for the patient, or when the clinican has a preference for one of the treatments. For such instances the suggestion is that the patient is randomly allocated to treatment only when there is clinical disagreement about treatment of choice for that patient, and then that patient is assigned to a clinican who had thought that the regimen allocated is the one most appropriate for that patient.