Primary sclerosing cholangitis. A report of 4 cases
Rodríguez, H.; Dehesa, M.; Aguirre García, J.; Blasco, J.M.
Revista de Gastroenterologia de Mexico 56(2): 71-75
1991
ISSN/ISBN: 0375-0906 PMID: 1947618 Document Number: 381316
We informed four cases of primary sclerosing cholangitis associated with chronic ulcerative colitis, diagnosed in the Gastroenterology Department, Hospital de Especialidades del CM Siglo XXI Mexico City, during 1987 to 1988. The mean age was 30.2 years and the evolution of colitis was 6.6 years. Two patients were females and two males, all presented active colitis and three presented hepatic symptoms. The laboratory abnormalities were hypertransaminasemia, increased alkaline phosphatase and hyperbilirubinemia. In three patients endoscopic retrograde cholangiopancreatography was done, in all cases diagnosis was established by histology. The frequency of primary sclerosing cholangitis associated with chronic ulcerative colitis was 13.3%.