Focused extracorporeal pyrotherapy. Initial experimental results

Vallancien, G.; Chopin, D.; Davila, C.; Guiillonneau, B.; Perreira, E.; Veillon, B.; Brisset, J.M.; Andre-Bougaran, J.

Progres en Urologie Journal de l'Association Francaise d'Urologie et de la Societe Francaise d'Urologie 1(1): 149-153

1991


ISSN/ISBN: 1166-7087
PMID: 1285392
Document Number: 380745
The objective of this study was to develop an apparatus allowing the generation of a high temperature (exceeding 80 degrees C) in a precise focus (20 mm x 2 mm) by means of extracorporeal elastic waves. The treatment time at high temperatures is brief and administered in sequences of 4 to 7 seconds. In vitro studies on blocks of polyurethane demonstrated melting of the plastic at the focal point. Studies on plastic spheres introduced into the bladder of the pig demonstrated melting of the sphere without any alteration in the tissues in the wave path. Studies of cellular viability of bladder carcinoma cultures demonstrated a significant difference after 48 hours between the non-treated control group and the group of cells submitted to high temperatures. This technique, called Pyrotherapy, should be promising if the preliminary results are confirmed.

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