Surgery in the treatment of pulmonary carcinoma with mediastinal lymph node metastasis (N2)
Quidaciolu, F.; Cappato, S.; Pastorino, G.; Guasone, F.; De Negri, A.; Giua, R.
Minerva Chirurgica 46(20): 1105-1108
1991
ISSN/ISBN: 0026-4733 PMID: 1662787 Document Number: 380721
This study is based on the analysis of the survival data in patients with N2 disease reported by Martini, Pearson, Shields et al. Many factors appear to influence survival of this group of patients. We made a retrospective analysis of a series of 91 patients with N2 disease between January 1980 and March 1985. Sixty-nine patients (71.5%) presented clinically N2 disease; 44 patients (63.7%) were treated with complete resection and postoperative irradiation, the actuarial five year survival was 11%. Twenty-two patients (24.2%) were discovered to have N2 disease at thoracotomy. Twenty-one patients underwent resection and the actuarial five year survival was 29%. We conclude that surgery can be effective in a highly selective group of patients.