Imipenem-cilastatin in the treatment of hospital infections
Mao, P.; Enrichens, F.; Olivero, G.; Sciascia, C.; Benedetto, G.; Franchello, A.; Olivero, S.
Journal of ChemoTherapy 3(Suppl 1): 205-207
1991
ISSN/ISBN: 1120-009X PMID: 12041766 Document Number: 379696
Imipenem was tested on 65 gram-negative bacterial strains consecutively isolated in patients affected by hospital infection and used as empiric therapy in 52 patients presenting a hospital infection suspected of gram-negative origin. More than 96% of the tested strains resulted sensitive to imipenem. This antibiotic showed a good clinical result in more than 80% of the cases when used as therapy. Therefore imipenem could be considered the drug of first choice in patients with a severe prognosis and a nosocomial infection suspected to be due to a gram-negative microorganism.
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