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Primary antiphospholipid syndrome: a report of two pediatric cases

Falcini, F.; Taccetti, G.; Trapani, S.; Tafi, L.; Petralli, S.; Matucci-Cerinic, M.

Journal of Rheumatology 18(7): 1085-1087

1991

ISSN/ISBN: 0315-162X
PMID: 1920312
Document Number: 377910
Two cases of primary antiphospholipid syndrome are described. A girl presented with myocardial infarction at the age of 6. afterward developed chorea, livedo reticularis, thrombocytopenia and circulating lupus anticoagulant (LAC). A boy, age 7, had an episode of intracranial hypertension and a deep venous thrombosis of a lower left limb, both recurrent in the following years. A high titer of IgG anticardiolipin antibodies (aCI) was detected. These observations suggest that both LAC and aCI tests should be performed in children with thromboembolic phenomena when the criteria for a definite autoimmune disease are lacking.

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