Experience with using etaperazine (perphenazine) in the treatment of patients with schizophrenia in a preschool psychiatric department
Proselkova, M.E.; Uzhanov, N.V.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 91(1): 120-122
1991
ISSN/ISBN: 0044-4588 PMID: 1647092 Document Number: 377473
The results of the treatment with perphenazine of 58 patients aged 5 to 7 years suffering from different forms of schizophrenia have been analyzed. Perphenazine was used in doses of 6 to 45 mg a day. The dosage was progressively increased until the optimal clinical effect was attained. The relationship was discovered between the range of psychopharmacological activity (from stimulating, organizing to antipsychotic and sedative) and the drug doses. The efficacy of the treatment with perphenazine correlated with the forms of schizophrenia, predominant syndromes in the disease clinical picture, and different stages of the process by the treatment commencement. Low toxicity and good tolerance of perphenazine, no pronounced side effects and complications were recorded. This made it possible to administer a wide range of the drug doses in the patients of the age group under study.