Re-examination of Rattus norvegicus as an animal model for Aeromonas-associated enteritis in man
Haberberger, R.L.; Yonushonis, W.P.; Daise, R.L.; Mikhail, I.A.; Ishak, E.A.
Experientia 47(5): 426-429
1991
ISSN/ISBN: 0014-4754 PMID: 2044691 Document Number: 377085
We have developed an oral feeding model for Aeromonas hydrophila enteritis using Rattus norvegicus with clindamycin pretreatment. All animals in the clindamycin group developed a self-limited, loose stool by day four of feeding. Intestinal examination revealed evidence of enteritis. Moreover, antibiotic usage may be a predisposing risk factor to infection.