Results of selected cytochemical studies of mature granulocytes in myelodysplastic syndromes and various other hematologic diseases
Mariańska, B.; Apel, D.; Maj, S.
Acta Haematologica Polonica 22(1): 54-57
1991
ISSN/ISBN: 0001-5814 PMID: 1823968 Document Number: 376224
The activity of alkaline phosphatase and peroxidase was measured in polymorphonuclears in 20 cases of myelodysplasia syndromes, 10 cases of chronic myeloid leukaemia. Reduced phosphatase activity was found in 5 cases and peroxidase activity in 3 cases of myelodysplasia syndromes. No evident correlation was noted between the activity of these enzymes and prognosis. Increased proportion of peroxidase-negative granulocytes was observed, moreover, in most cases of chronic myeloid leukaemia. The observations will be continued in larger material.