Structure of respiratory allergens
Jäger, L.
Allergie et Immunologie 23(7): 274-279
1991
ISSN/ISBN: 0397-9148 PMID: 1720620 Document Number: 375949
Respiratory allergens from one of the most important group of allergens. Except for professional allergens they are characterized by an enormous heterogeneity including a restricted number of major allergens. By means of modern immunological, chemical and genetic techniques some of them are, at least partially, characterized. Immunogenicity depends on a restricted area of the molecules. These epitopes seem to be in principle different for B cells (antibodies) and T cells. The strategies to improve immunodiagnosis are, therefore, not necessarily identical with those for the development of immunotherapy. The present data on selected respiratory allergens are summarized.