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Lack of agreement of chromogenic and clotting assays for factor X and protein C in warfarinised plasma

Han, P.; Fung, K.P.; Rahdakrishnan, U.

Thrombosis and Haemostasis 65(4): 360-363

1991

ISSN/ISBN: 0340-6245
PMID: 2057917
Document Number: 375273
Coagulation serine proteases can be measured with either a chromogenic substrate assay or a clotting assay using deficient plasmas. It is a concern whether both assays give similar quantitative results, in particular in plasma obtained from patients on long term warfarin therapy. If these two assay methods were interchangeable, then the chromogenic substrate assay has the advantages of precision as well as laboratory automation. We used the intraclass correlation coefficient (rI) to assess the agreement between the two methods in measuring factor X and protein C levels in warfarinised plasma. The results indicate that the extent and pattern of agreement of the two methods for the measurement of the two variables in warfarinised plasma are poor, despite high Pearson product moment coefficients of correlation.

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Katagiri, H.; Itoh, S.; Uchida, T.; Kawai, Y.; Watanabe, K. 1999: Monitoring of plasma concentration of low molecular weight heparin--comparative evaluation with chromogenic and clotting assays Rinsho Byori. Japanese Journal of Clinical Pathology 47(11): 1046-1051
Christensen, U. 1980: Requirements for valid assays of clotting enzymes using chromogenic substrates Thrombosis and Haemostasis 43(2): 169-174
Lee, C.A.; Owens, D.; Bray, G.; Giangrande, P.; Collins, P.; Hay, C.; Gomperts, E.; Schroth, P.; Barrowcliffe, T. 1999: Pharmacokinetics of recombinant factor VIIi (recombinate) using one-stage clotting and chromogenic factor VIIi assay Thrombosis and Haemostasis 82(6): 1644-1647
Kitchen, S.; Preston, F.E. 1993: Factor VIi clotting assays: influence of thromboplastin Thrombosis and Haemostasis 70(4): 720
Paolucci, F.; Frasa, H.; Aarle, F.V.; Capdevla, A.; Marie-Clavies, C.; Theo van Dinther; Yvonne, F.Hendriks, D.; Michiel van den Heuvel; Nadal, T.; Lagrange, F.; Necciari, J.; Perez, Y. 2003: Two Sensitive and Rapid Chromogenic Assays of Fondaparinux Sodium (Arixtra®)in Human Plasma and Other Biological Matrices Clinical Laboratory 49(9-10): 451-460
Jennings, I.; Kitchen, S.; Woods, T.A.; Preston, F.E. 1999: Normalization does not improve between-laboratory agreement but may improve specificity of some assays for activated protein C resistance Blood Coagulation and Fibrinolysis: An International Journal in Haemostasis and Thrombosis 10(7): 451-453
Bairova, T.A.; Gommellya, M.V.; Dolgich, V.V.; Philippov, E.S.; Kolesnikova, L.I. 2016: Polymorphism (353)R>Q of Gene of Blood Clotting Factor FVIi and Plasma Hemostasis Genetika 52(2): 242-248
Chmielewska, J.; Latallo, Z.S. 1982: Experience with chromogenic substrates in studies of clotting and fibrinolytic systems Folia Haematologica 109(1): 111-114
Sonder, S.A.; Fenton, J.W. 1986: Thrombin specificity with tripeptide chromogenic substrates: comparison of human and bovine thrombins with and without fibrinogen clotting activities Clinical Chemistry 32(6): 934-937
Rock, G.; Palmer, D.S. 1985: Disparity between one- and two-stage factor VIIi assays in measuring VIIIC in heparinized plasma Thrombosis and Haemostasis 54(4): 780-783
Lanevschi, A.; Kramer, J.W.; Greene, S.A.; Meyers, K.M. 1996: Evaluation of chromogenic substrate assays for fibrinolytic analytes in dogs American Journal of Veterinary Research 57(8): 1124-1130
Auer, J.W.; Berent, R.; Eber, B. 2001: Lack of association of increased C-reactive protein and total plasma homocysteine Circulation 104(25): E164
Lee, C.; Barrowcliffe, T.; Bray, G.; Gomperts, E.; Hubbard, A.; Kemball-Cook, G.; Lilley, P.; Owens, D.; Von Tilberg, L.; Pasi, J. 1996: Pharmacokinetic in vivo comparison using 1-stage and chromogenic substrate assays with two formulations of Hemofil-M Thrombosis and Haemostasis 76(6): 950-956
Narahara, N.; Uchiyama, T.; Andoh, K.; Tanaka, H.; Kobayashi, N. 1989: Interaction of plasma clotting factors with vascular endothelial cells in hemostasis and thrombosis with special reference to endothelial cell tissue factor Nihon Ketsueki Gakkai Zasshi: Journal of Japan Haematological Society 52(8): 1330-1336
Kristensen, B.K.; Jakobsen, D.F.; Hansen, A.M.; Mogensen, S.; Fuglsang, W.; Schur, K.; Rasmussen, K.D.; Mortensen, B.M.; Larsen, G. 1978: Not a lack of will but of agreement about what there should be Sygeplejersken 78(10): 11; 22
Hemker, H.C.; Kop, J.; Willems, G.M. 1979: Kinetic aspects of the interaction of blood clotting enzymes. VIII. the relation between clotting time and clotting velocity Thrombosis and Haemostasis 41(2): 309-313
Roth, E.; Funovics, J.; Karner, J.; Huk, I.; Schulz, F.; Fritsch, A. 1983: Lack of stimulation of nitrogen retention and plasma protein synthesis due to increased intake of branched-chain amino acids Infusionstherapie und Klinische Ernahrung 10(5): 259-266
Hiura, H.; Nishiyama, T.; Kimura, M.; Matoba, K.; Hayashi, O.; Sasaki, M.; Ishijima, C.; Irie, Y.; Yasuda, N. 1989: Recent progress on analysis of blood coagulation factors and fibrinolytic agents; new synthetic chromogenic substrate assays for hemostatic parameters Rinsho Byori. Japanese Journal of Clinical Pathology Spec no 81: 214-219
Neuser, J. 1987: Lack of agreement of projective and objective tests is not an indication of deficient validity Psychotherapie Psychosomatik Medizinische Psychologie 37(12): 431-432
Guevara Eslava, M.; Cuñado Barrio, A.; García López, F. 2001: Lack of agreement between home self-determination and ambulatory monitoring of blood pressure Medicina Clinica 116(18): 719