Keratin phenotype of the human thymus gland epithelium in the pre- and postnatal periods

Karelina, T.V.; Kalinina, I.I.

Biulleten' Eksperimental'noi Biologii i Meditsiny 111(1): 87-90

1991


ISSN/ISBN: 0365-9615
PMID: 1711386
Document Number: 374007
Comparative immunomorphological data were presented on the distribution of keratin-expressing cells in the human thymus during the pre- and postnatal development periods. The study was conducted using monoclonal antibodies to individual keratins of various histological specificity. Based on a set of the monoclonal antibodies to individual keratin proteins used in the experiment, the kerain phenotype of most of the cells of the thymic epithelial reticulum is close to the keratin phenotype of nondifferentiated basal cells of embryonic epidermis before the stratification and formation of its appendages begin.

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