High dose rate intracavitary radiation therapy of carcinoma of the cervix using a linear source
Azhar, T.; Kamada, T.; Lopez, F.; Harun, R.; Nor, I.M.; Lim, A.
Medical Journal of Malaysia 46(2): 123-128
1991
ISSN/ISBN: 0300-5283 PMID: 1839415 Document Number: 372575
One hundred patients with carcinoma of the cervix stages 1B to 4A were treated with intracavitary high dose rate radiation using a linear cobalt source. All cases have received external beam pelvic irradiation to 4500cGy mid plane in twenty fractions over four weeks. The results in terms of patient compliance and convenience were good while acute and late morbidities were comparable to standard Manchester technique of low dose rate intracavitary therapy as practised in the Institute of Radiotherapy and Oncology General Hospital Kuala Lumpur. The four year actuarial survival rate is 76% for stage II and 48% for stage III. All three stage IV patients died within 1 year. Four out of seven stage I patients are alive (minimum follow-up 18 months, longest 43 months). One died of systemic spread at 33 months while one is lost to follow up.