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Linear IgA dermatosis of childhood

Witkamp, L.; Smitt, J.H.

British Journal of Dermatology 125(4): 395-396

1991

ISSN/ISBN: 0007-0963
PMID: 1954138
Document Number: 369602
In a six-year-old girl with linear IgA dermatosis of childhood there were lesions with typical rosette like configuration, crusted erosions and isolated bullae on apparently normal skin. The histopathology revealed subepidermal blister and superficial perivascular lymphohistiocytic infiltrate with many neurophils and some eosinophils. Direct immunofluorescence examination showed linear deposits of IgA along the basal membrane zone. Circulating antibodies were absent. Therapy with dapsone in a dose of 25 mg/day was effective.

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