Favorable course of pregnancy in a patient two years after kidney transplantation
Szepietowski, T.; Ujec, M.; Falkiewicz, K.; Bielanow, T.; Szczepański, A.
Polski Tygodnik Lekarski 46(4-5): 84-86
1991
ISSN/ISBN: 0032-3756 PMID: 1845702 Document Number: 369041
A 30-year old female underwent kidney transplantation after unsuccessful 3-year dialysis for renal cortex necrosis. Immunosuppression was achieved with cyclosporin followed by azathioprine with prednisone. The patient conceived after 22 months with kidney transplantation. Mild decrease in arterial blood pressure and marked increased in glomerular filtration rate were seen during the first three months of pregnancy. Arterial blood pressure increased but insignificantly at the end of pregnancy. That time, gradual decrease in creatinine clearance was observed. An increase in serum bilirubin and alkaline phosphatase was noted. Pregnancy was terminated by cesarean section on the 38th week. Newborn was female, full-termed, viable, with body weight of 3,300 g. All examined parameters were normalized after delivery. Described case indicates that transplanted kidney functioning during pregnancy is similar to that in healthy women.