Immunoelectroblotting in Mexican subjects at high risk for infection with human immunodeficiency virus (HIV)
Flores-Castañeda, M.S.; Salinas-Carmona, M.C.; Yáñez-Rodríguez, A.
Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 43(3): 229-233
1991
ISSN/ISBN: 0034-8376 PMID: 1818369 Document Number: 369019
Sera from 124 persons in high risk groups were analyzed including homosexuals, blood recipients, and spouses or siblings from AIDS patients. In this study, 118 individuals had a positive ELISA for anti-HIV antibodies. Six persons had a complete immunodeficiency syndrome and a negative ELISA test. In the Western blot, 111 sera were positive, four negative, and nine scored indeterminate; four of the latter converted to positive when retested three months later. Antibodies present in the positive sera were directed against the HIV gp 41 kD in 100% of the cases and against the gp 120 kD in 82%. Frequency of recognition of p55 kD was 96% but p18 kD was only 42%.