Treatment of chronic hepatitis B with interferon alfa-2b (Intron A)
Cianciara, J.; Laskus, T.; Hryniewicz, H.; Jabłońska, J.; Loch, T.
Przeglad Epidemiologiczny 45(4): 315-320
1991
ISSN/ISBN: 0033-2100 PMID: 1841409 Document Number: 368779
Eighteen patients with biopsy proven chronic hepatitis B and markers of ongoing viral replication were treated with interferon alpha-2b (Intron A) while 24 similar patients served as control group. Permanent termination of HBV replication and normalization of ALT and AST activity was seen in 7 (39%) treated patients and in only two (8%) controls (p less than 0.05). Adverse reactions were few and subsided with the termination of therapy. These results of interferon therapy in chronic hepatitis B seem encouraging.
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